Spherical Agglomeration: A Novel Technique Of Particulate Modification & Developing Niche Drug Delivery System

Present review on the topic explores the different techniques of spherical agglomeration employed in pharmaceutical sciences and their potential applications in developing new particulate systems of drug. Spherical agglomeration is a particle engineering technique which transforms the fine crystals into spherical particles in a single step. These techniques applied in development of new systems of drug delivery. Using various techniques of spherical agglomeration, several drugs have been modified for micromeritics, compression properties as well as solubility and dissolution of poorly soluble drugs. Different methods of characterization of spherical agglomeration were also examined. These techniques have been used to modify pharmaceutical processing, drug product performances and bioavailability issues.